Flavokawain B
CAS No. 1775-97-9
Flavokawain B ( Flavokawain B; Flavokawain-B; FlavokawainB )
产品货号. M12673 CAS No. 1775-97-9
Flavokawain B is a natural chalcone that can induce apoptosis in androgen receptor-negative, hormone-refractory prostate cancer cell lines (IC50=3-50 uM).
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥1320 | 有现货 |
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10MG | ¥2130 | 有现货 |
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25MG | ¥3621 | 有现货 |
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50MG | ¥5233 | 有现货 |
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100MG | ¥7193 | 有现货 |
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500MG | ¥14499 | 有现货 |
|
1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Flavokawain B
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Flavokawain B is a natural chalcone that can induce apoptosis in androgen receptor-negative, hormone-refractory prostate cancer cell lines (IC50=3-50 uM).
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产品描述Flavokawain B is a natural chalcone that can induce apoptosis in androgen receptor-negative, hormone-refractory prostate cancer cell lines (IC50=3-50 uM), via up-regulation of death-receptor 5 and Bim expression; induces apoptosis in human myeloid leukemic cells by modifying NF-κB, possesses potential anti-inflammation and anti-cancer activities; also exhibits significant inhibition of the neurogenic nociceptive induced by intraplantar injections of glutamate and capsaicin in mice.
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同义词Flavokawain B; Flavokawain-B; FlavokawainB
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通路Apoptosis
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靶点Apoptosis
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受体Others
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研究领域——
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适应症——
化学信息
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CAS Number1775-97-9
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分子量284.31
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分子式C17H16O4
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纯度>98% (HPLC)
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溶解度Chloroform: Soluble Dichloromethane: SolubleEthyl Acetate: SolubleAcetone: SolubleDMSO: 38 mg/mL (133.7 mM) ( < 1 mg/ml refers to the product slightly soluble or insoluble )
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SMILESO=C(C1=C(OC)C=C(OC)C=C1O)/C=C/C2=CC=CC=C2
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化学全称2-Propen-1-one, 1-(2-hydroxy-4,6-dimethoxyphenyl)-3-phenyl-, (E)-
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Tang Y, et al. Int J Cancer. 2010 Oct 15;127(8):1758-68.
2. Lee JJ, et al. Anticancer Res. 2018 May;38(5):2771-2778.
3. Mohamad AS, et al. Eur J Pharmacol. 2010 Nov 25;647(1-3):103-9.
4. Abu N, et al. Nat Prod Commun. 2015 Jul;10(7):1199-202.
2. Lee JJ, et al. Anticancer Res. 2018 May;38(5):2771-2778.
3. Mohamad AS, et al. Eur J Pharmacol. 2010 Nov 25;647(1-3):103-9.
4. Abu N, et al. Nat Prod Commun. 2015 Jul;10(7):1199-202.
产品手册
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